What are the Benefits of CBD oil?
Benefits and Uses of CBD Oil (Plus Side Effects) Cannabidiol is a popular natural remedy for many ailments. Better known as CBD, it is one of over 100 chemical compounds known as cannabinoids found in the cannabis or marijuana plant, Cannabis sativa (1Trusted Source). Tetrahydrocannabinol (THC) is the primary psychoactive cannabinoid found in cannabis and causes the sensation of getting “high” that’s often associated with marijuana. However, unlike THC, CBD is not psychoactive.
This quality makes CBD an appealing option for those who are looking for relief from pain and other symptoms without the mind-altering effects of marijuana or certain pharmaceutical drugs.
CBD oil is made by extracting CBD from the cannabis plant and then diluting it with a carrier oil like coconut or hemp seed oil. It’s gaining momentum in the health and wellness world, with some scientific studies confirming it may ease symptoms of ailments like chronic pain and anxiety. Here are seven health benefits of CBD oil backed by scientific evidence.
Can Relieve Pain Marijuana has been used to treat pain as far back as 2900 B.C. (2Trusted Source). More recently, scientists have discovered that specific components of marijuana, including CBD, are responsible for its pain-relieving effects.
The human body contains a specialized system called the endocannabinoid system (ECS), which is involved in regulating various functions, including sleep, appetite, pain, and immune system response (3Trusted Source).
The body produces endocannabinoids, neurotransmitters that bind to cannabinoid receptors in your nervous system.
Studies have shown that CBD may help reduce chronic pain by impacting endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters (4Trusted Source). For example, one study in rats found that CBD injections reduced pain response to surgical incisions. In contrast, another rat study found that oral CBD treatment significantly reduced sciatic nerve pain and inflammation.
(5Trusted Source, 6Trusted Source).
Several human studies have found that a combination of CBD and THC is effective in treating pain related to multiple sclerosis and arthritis. An oral spray called Sativex, which is a combination of THC and CBD, is approved in several countries to treat pain related to multiple sclerosis.
One study of 47 people with multiple sclerosis examined the effects of taking Sativex for one month. The participants experienced improvements in pain, walking, and muscle spasms. Still, the study didn’t include any control group, and the placebo effects could not be ruled out (7Trusted Source). Another study found that Sativex significantly improved pain during movement, pain at rest and sleep quality in 58 people with rheumatoid arthritis
2. Could Reduce Anxiety and Depression
Anxiety and depression are common mental health disorders that can have devastating impacts on health and well-being. According to the World Health Organization, depression is the single most significant contributor to disability worldwide, while anxiety disorders are ranked sixth (9). Anxiety and depression are usually treated with pharmaceutical drugs, which can cause several side effects, including drowsiness, agitation, insomnia, sexual dysfunction and headache (10Trusted Source).
What’s more, medications like benzodiazepines can be addictive and may lead to substance abuse (11Trusted Source).CBD oil has shown promise as a treatment for both depression and anxiety, leading many who live with these disorders to become interested in this natural approach.
In one Brazilian study, 57 men received either oral CBD or a placebo 90 minutes before they underwent a simulated public speaking test. The researchers found that a 300-mg dose of CBD was the most effective at significantly reducing anxiety during the test.
The placebo, a 150-mg dose of CBD, and a 600-mg dose of CBD had little to no effect on anxiety (12Trusted Source).
CBD oil has even been used to safely treat insomnia and anxiety in children with post-traumatic stress disorder (13Trusted Source). In several animal studies, CBD has also shown antidepressant-like effects (14Trusted Source, 15Trusted Source).
These qualities are linked to CBD’s ability to act on the brain’s receptors for serotonin, a neurotransmitter that regulates mood and social behaviour. Can Alleviate Cancer-Related Symptoms CBD may help reduce symptoms related to cancer and side effects related to cancer treatment, like nausea, vomiting and pain. One study looked at the effects of CBD and THC in 177 people with cancer-related pain who did not experience relief from pain medication.
Those treated with an extract containing both compounds experienced a significant reduction in pain compared to those who received only THC extract (16Trusted Source). CBD may also help reduce chemotherapy-induced nausea and vomiting, which are among the most common chemotherapy-related side effects for those with cancer (17Trusted Source).
Though there are drugs that help with these distressing symptoms, they are sometimes ineffective, leading some people to seek alternatives.
A study of 16 people undergoing chemotherapy found that a one-to-one combination of CBD and THC administered via mouth spray reduced chemotherapy-related nausea and vomiting better than standard treatment alone (18Trusted Source).
Some test-tube and animal studies have shown that CBD may have anticancer properties. For example, one test-tube study found that concentrated CBD induced cell death in human breast cancer cells (19Trusted Source). Another study showed that CBD inhibited the spread of aggressive breast cancer cells in mice (20Trusted Source). However, these are test-tube and animal studies, so they can only suggest what might work in people. More studies in humans are needed before conclusions can be made.4
4 May Reduce AcneAcne is a common skin condition that affects more than 9% of the population (21Trusted Source). It is thought to be caused by several factors, including genetics, bacteria, underlying inflammation and the overproduction of sebum, an oily secretion made by sebaceous glands in the skin (22Trusted Source, 23).
Based on recent scientific studies, CBD oil may help treat acne due to its anti-inflammatory properties and ability to reduce sebum production. One test-tube study found that CBD oil prevented sebaceous gland cells from secreting excessive sebum, exerted anti-inflammatory actions and prevented the activation of “pro-acne” agents like inflammatory cytokines (24Trusted Source).
Another study had similar findings, concluding that CBD may be an efficient and safe way to treat acne, thanks partly to its remarkable anti-inflammatory qualities (25Trusted Source). Though these results are promising, human studies exploring the effects of CBD on acne are needed.
5 Might Have Neuroprotective Properties
CBD’s ability to act on the endocannabinoid system and other brain signalling systems may benefit those with neurological disorders. In fact, one of the most studied uses for CBD is treating neurological disorders like epilepsy and multiple sclerosis. Though research in this area is still relatively new, several studies have shown promising results.
Sativex, an oral spray consisting of CBD and THC, has been proven to be a safe and effective way to reduce muscle spasticity in people with multiple sclerosis.
One study found that Sativex reduced spasms in 75% of 276 people with multiple sclerosis who were experiencing muscle spasticity that was resistant to medications (26Trusted Source). Another study gave 214 people with severe epilepsy 0.9–2.3 grams of CBD oil per pound (2–5 g/kg) of body weight. Their seizures were reduced by a median of 36.5% (27Trusted Source).
One more study found that CBD oil significantly reduced seizure activity in children with Dravet syndrome, a complex childhood epilepsy disorder, compared to a placebo (28Trusted Source).
However, it’s important to note that some people in both these studies experienced adverse reactions associated with CBD treatment, such as convulsions, fever and fatigue. CBD has also been researched for its potential effectiveness in treating several other neurological diseases.
For example, several studies have shown that treatment with CBD improved the quality of life and sleep quality for people with Parkinson’s disease (29Trusted Source, 30Trusted Source). Additionally, animal and test-tube studies have shown that CBD may decrease inflammation and help prevent the neurodegeneration associated with Alzheimer’s disease (31 Trusted Source). In one long-term study, researchers gave CBD to mice genetically predisposed to Alzheimer’s disease, finding that it helped prevent cognitive decline.
Could Benefit Heart Health
Recent research has linked CBD with several heart and circulatory system benefits, including lowering high blood pressure.
High blood pressure is linked to higher risks of several health conditions, including stroke, heart attack, and metabolic syndrome (33Trusted Source). Studies indicate that CBD can help with high blood pressure. One recent study treated nine healthy men with one dose of 600 mg of CBD oil and found it reduced resting blood pressure compared to a placebo.
The same study also gave the men stress tests that typically increase blood pressure. Interestingly, the single dose of CBD led the men to experience a more minor blood pressure increase than usual in response to these tests (34Trusted Source). Researchers have suggested that CBD’s stress—and anxiety-reducing properties are responsible for its ability to help lower blood pressure.
Additionally, several animal studies have demonstrated that CBD may help reduce the inflammation and cell death associated with heart disease due to its powerful antioxidant and stress-reducing properties. For example, one study found that treatment with CBD reduced oxidative stress and prevented heart damage in diabetic mice with heart disease
7 Several Other Potential Benefits CBD has been studied for its role in treating several health issues other than those outlined above. Though more studies are needed, CBD is thought to provide the following health benefits: Antipsychotic effects: Studies suggest that CBD may help people
with schizophrenia and other mental disorders by reducing psychotic symptoms (36Trusted Source). Substance abuse treatment: CBD has been shown to modify circuits in the brain related to drug addiction. In rats, CBD has been shown to reduce morphine dependence and heroin-seeking behaviour (37Trusted Source).
Anti-tumour effects: CBD has demonstrated anti-tumour effects in test-tube and animal studies. In animals, it has been shown to prevent the spread of breast, prostate, brain, colon, and lung cancer (38Trusted Source). Diabetes prevention: In diabetic mice, treatment with CBD reduced the incidence of diabetes by 56% and significantly reduced inflammation (39 Trusted Source).
Disclaimer: This article is originally published on https://www.healthline.com/nutrition/cbd-oil-benefits
