A new study has shown that pre-treatment CBD may have a neuroprotective effect in stroke patients.
The Study aimed to investigate the effect of CBD on oxidative stress and cell death, which occurs in ischemic stroke patients.
It revealed that the cannabinoid may reduce the destructive effects of cell damage associated with stroke.
Ischemic strokes are the most common type of stroke. They occur when a blood clot blocks oxygen or blood flow to the brain. This happens in arteries narrowed or blocked by fatty deposits (plaques) over time. The most common symptoms of a stroke include facial drooping on one side, not being able to lift your arms and slurred speech.
If this occurs, a person must be immediately taken to the emergency room.
The National Institute of Health Care and Excellence (NICE) estimates around 100,000 strokes annually in the UK. It is also thought that 1.3 million people live with the effects of a stroke.
Stroke recovery and CBD results
The Study showed that CBD reduced the amount of infarction in those samples that had been given the cannabinoid. Infarction refers to the death of tissue due to a lack of blood supply and is commonly due to a blood vessel being obstructed or narrowed.
There were also differences in malondialdehyde level (MDA) – a standard marker of oxidative stress – between the brains of the CBD and vehicle groups.
It also revealed that CBD may help to protect tissue by preventing further damage.
THC and stroke risk
Another recent study examined the effect that tetrahydrocannabinol (THC) could have on strokes. It found that it may increase the risk of a specific type of stroke among cannabis consumers.
According to findings, cannabis consumers who experience a stroke, known as an aneurysmal subarachnoid haemorrhage (aSAH), are twice as likely to develop further complications.
An aSAH occurs when a weakened blood vessel bursts on the brain’s surface, leading to bleeding between the brain and the tissue covering it. It can result in neurological disabilities, long-term slurred speech or even death. It is estimated that aSAH affects around eight people per 100,000 of the population each year, accounting for six per cent of first strokes.
The Study by the American Stroke Association suggested there is twice the risk of developing delayed cerebral ischemia for cannabis consumers. The researchers analyzed data from 1,000 patients who had received treatment for bleeding over 12 years. In the group of participants, 36 per cent developed cerebral ischemia, and 50 per cent had moderate to severe disabilities.
When comparing the results of patients who tested positive for THC with those who did not, they found cannabis consumers were 2.7 times more likely to develop cerebral ischemia. They were also 2.8 times more likely to create long-term moderate to severe physical disabilities.
However, compared to those who tested negative for THC, the cannabis group did not have more giant aneurysms, higher blood pressure or worse stroke symptoms when admitted to the hospital. They did not have any higher cardiovascular risk factors than the opposing group.
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